Human Chorionic Gonadrotropin 2000iu
by Bill Roberts – HCG (human chorionic gonadotropin) is provided as a glycoprotein
powder to be diluted with water and taken by injection, either
intramuscularly or subcutaneously. It acts in the body like
luteinizing hormon(LH), stimulating the testes to produce testosterone even when natural LH is not present or is deficient.
It therefore is useful for maintaining testosterone production
and/or testicle size during a steroid cycle.
Additionally, outside of or in-between steroid cycles, it can be
very useful for increasing testosterone production. The success of
this depends on the ability of the testes to actually produce
greater amounts of testosterone with increased stimulation. Where
the testes themselves are the limiting factor, HCG cannot overcome
Including HCG as part of a hormone replacement therapy (HRT)
program is superior to relying on testosterone alone if maintenance
of sperm production and/or normal testicle size is considered
important. Use of testosterone alone can result in infertility or
reduced fertility, as normal testicular function depends on higher
intratesticular testosterone levels than results from such use.
With regard to steroid usage, HCG should either not be used as part
of post-cycle therapy (PCT) at all, or should be used only in a
rather precise manner to avoid impeding recovery, shortly to be
Post-cycle recovery of LH production requires androgen levels to
have fallen back into the physiological range. With use of medium
or long-acting esters, this is a slow process. For example, let’s
suppose that a given testosterone ester’s half-life is 7 days, and
that 800 mg/week was used during the cycle. If so, then one week
after the last injection, levels will be similar to what they would
be if 400 mg had been taken weekly for some time, and with another
400 mg having just been injected. At the two week point after the
last injection, levels will be commensurate with ongoing 200
This is without using HCG during this period.By this point,
ordinarily some recovery could begin with use of Clomid or
But if HCG were used during this time, or started at this point,
testosterone levels would be similar not to those of ongoing 200
mg/week usage, but to that level plus another 100-200 mg/week of
equivalent increase from HCG. This would interfere with recovery of
The better plan is, if using HCG, to employ it during a cycle to
maintain testicular function so that the testes will be responsive
to LH as soon as its production is restored. There will also be the
advantages of maintaining testicle size and of providing some
additional testosterone via HCG-stimulated production.
This last point will be of no great importance when a large amount
of steroids is being used weekly, but can be quite significant if
the total milligram amount is modest.
Such added testosterone production is of particular value if a
stack is entirely non-aromatizing and dosed high enough to be fully
inhibitory of natural testosterone production. In that situation,
estrogen levels would fall abnormally low unless or HCG is taken to
yield normal testosterone levels during the cycle, as estradiol is
produced from testosterone.
The traditional HCG dose was 2000 IU at a time. While this produces
blood levels representing a vast overdose for at least the first
week after injection, this dosage had a medical use as in many
cases it is desirable to administer only a single injection, or
infrequent injections, than to require two or more office visits
per week for injection. And as the half life is only a few days, an
extremely high initial level is required to obtain extended
duration of action from a single injection.
This dosage is far more than should ever be used in bodybuilding or
for hormone replacement therapy.
My previous recommendation of 500 IU/day as being generally
sufficient was a radical break from bodybuilding practice at the
time, which employed far higher doses that gave HCG a reputation as
a harsh drug; but further experience as well as a medical study on
the matter published in 2005 by Coviello et al. has shown that even
less than that is needed.
Little if any difference exists in resulting testosterone
production between dosings of 250 IU every other day (EOD) and 500
IU EOD. Dr Eugene Shippen has also found low-dose use effective in
extensive clinical practice, and bodybuilding practice has also
shown such doses to be completely effective.
Accordingly I now consider a dosage of 500 IU EOD (or 3x/week,
which is nearly equivalent), or 250 IU daily to represent a
reasonable absolute maximum.
As values for general use, 100 IU daily, 200 IU EOD, or 250 IU
three times per week are very effective. The medical study
mentioned above found no significant difference in results between
this dosage level and the above recommended absolute maximum, but
it may be the case that for some individuals there could be some
At these doses, unlike what is the case with vast overdoses, HCG
has no perceptible side effects.
As a part of PCT, as already explained HCG should not be used
during that period in which inhibition would result from the
combination of the resulting testosterone production and the
remaining levels of injected steroid. However, upon levels of
injected steroid falling below what would be commensurate with 100
mg/week use, very low dose HCG such as 100-125 IU every other day
is acceptable as a part of PCT.